Another reason for unexplained weight gain in women can be polycystic ovarian syndrome. While PCOS sounds like a condition affecting the ovaries, don’t be fooled, it is an endocrine disorder that affects several different systems. Depending on your case history we may refer you for salivary hormone testing to investigate the state of your hormones. The good news is that the Keto diet is the perfect nutritional program to correct the endocrine disruption associated with PCOS.